| Customization: | Available |
|---|---|
| CAS No.: | 98-79-3 |
| Formula: | C5h7no3 |
|
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Product Name |
Pyroglutamic Acid |
EINECS No. |
202-700-3 |
|
CAS No. |
98-79-3 |
Purity |
98%min |
|
MF |
C5H7NO3 |
Appearence |
White Crystal Powder |
L-Pyroglutamic acid is a derivative of the amino acids glutamine and glutamic acid. L-Pyroglutamic acid also known by other names such as pyroglutamate, 5-oxoproline and pidolic acid.
L-Pyroglutamic acid is a nonessential nutrient, meaning that the body normally biosynthesizes adequate quantities of pyroglutamic acid. It is typically formed in the body as a by-product of the glutathione cycle, in which the enzyme 5-oxoprolinase acts upon glutamic acid. Some pyroglutamic acid also forms when glutamine or glutamic acid spontaneously cyclizes. Pyroglutamic acid is available from a variety of dietary sources, including fruits and vegetables. Bacteriorhodopsin is one of the many proteins that contain pyroglutamic acid as a component.
Pyroglutamic acid has two specific forms known as enantiomers. These include D-pyroglutamic acid and L-pyroglutamic acid, with L-pyroglutamic acid being the biologically active enantiomer in humans. The primary biochemical use of L-pyroglutamic acid is believed to be increasing the activity of the neurotransmitter acetylcholine. L-Pyroglutamic acid may also be used in the production of the neurotransmitters gamma-aminobutyric acid (GABA) and glycine.
Acetylcholine acts on both the central nervous system and peripheral nervous system. It is also the only neurotransmitter that affects the motor portion of the somatic nervous system. Furthermore, acetylcholine is the primary neurotransmitter for the autonomic ganglia.
1.Pyroglutamic acid is one of the main components of the skin's natural moisturizing factor, and its moisturizing ability far exceeds that of glycerin and propylene glycol. It is non-toxic and non-irritating, and is an excellent raw material for modern skin care and hair care cosmetics.
2.Pyroglutamic acid also inhibits the activity of tyrosine oxidase, thereby preventing the deposition of "melanoid" substances in the skin and whitening the skin.
3.It has a softening effect on keratin and can be used in nail cosmetics.
4.In addition to its application in cosmetics, L-pyroglutamic acid can also form derivatives with other organic compounds, which have special effects in surface activity, transparent light and so on.
5.Can also be used as a surfactant for detergents; chemical reagents for the resolution of racemic amines; organic intermediates.
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