Antiprotozoal Raw Material CAS 58-14-0 High Puirty 99% Pyrimethamine

• Customization: Available
• CAS No.: 58-14-0
• Formula: C12h13cln4
• Model NO.: LYPH-Pyrimethamine
• EINECS: 200-364-2
• Type: Pharmaceutical Intermediates
• Appearance: White Fine Powder
• Quality: Medicine Grade
• Colour: White
• Product Name: Pyrimethamine
• Other Name: 2, 4-Diamino-5-(P-Chlorophenyl)-6-Ethylpyrimidine
• Sample Order: Accept
• Test Mothod: HPLC
• Certificate: ISO
• Factory: Yes
• Storage Condition: Cool Dry Place
• MW: 248.7114
• Shelf Life: 2 Years
• Function: Healthcare Supplement
• Stocks: Available
• OEM: Accept
• After Sale Service: Yes
• Water Solubility: 0.01 G/100 Ml
• Density: 1.305g/cm3
• Transport Package: Foil Bag/Fiber/Carton Box
• Specification: 98%, 99%
• Trademark: Lyphar
• Origin: China
• HS Code: 2933990099
• Production Capacity: 1000kg/Month

Product Description

Antiprotozoal Raw Material CAS 58-14-0 High Puirty 99% Pyrimethamine 

 

Product name: Pyrimethamine 
CAS No: : 58-14-0
Specifications: 99% (HPLC)
Molecular formula:  C12H13ClN4
Molecular: 248.7114
Appearance:White Fine Powder

Pyrimethamine is a diaminopyrimidine which is structurally related to trimethoprim. It is effective against erythrocytic stage of Plasmodium (P) falciparum and less so against P. vivax, P. ovale and P. malariae. Pyrimethamine also inhibits the sporogony in the mosquito, resulting in a decrease of transmission of the infection within the community. The mechanism of action of pyrimethamine is related to its inhibition of dihydrofolic reductase necessary for the folic acid synthesis in the parasite. Lyphar Biotech supply Pyrimethamine  since 2011.Pyrimethamine acts slowly and is not recommended as monotherapy for acute malaria attacks. Resistance to pyrimethamine developed soon when the drug was used on a large scale as monoprophylaxis.